Search results for "Middle East respiratory syndrome"

showing 6 items of 6 documents

Awareness of droplet and airborne isolation precautions among dental health professionals during the outbreak of corona virus infection in Riyadh cit…

2015

Background This study aimed to determine knowledge, attitude and practice of airborne and droplet isolation precautions among Dental Health Professionals (DHPs) (dental students, interns, practitioners and auxiliaries) during the outbreak of MERS (Middle East Respiratory Syndrome), corona virus infection in Riyadh city, Saudi Arabia. Material and Methods A cross-sectional survey was conducted among 406 dental health professionals (DHPs) working in selected dental facilities in Riyadh city, Saudi Arabia during the outbreak of MERS (April-June 2013). A structured, close-ended, self-administered questionnaire explored the knowledge, attitude, and practice towards droplet and isolation precauti…

medicine.medical_specialtyPediatricseducationOdontologíaDental FacilitiesDHPS03 medical and health sciences0302 clinical medicineIsolation precautionsmedicine030212 general & internal medicineGeneral DentistryResponse rate (survey)Descriptive statisticsbusiness.industryResearchDental healthOutbreak030206 dentistrymedicine.diseaseCiencias de la saludCommunity and Preventive DentistryFamily medicineUNESCO::CIENCIAS MÃ DICASMiddle East respiratory syndrome:CIENCIAS MÃ DICAS [UNESCO]businessJournal of Clinical and Experimental Dentistry

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Learning from history: Coronavirus outbreaks in the past

2020

2019-20 coronavirus outbreakbiologybusiness.industryMiddle East respiratory syndrome coronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)OutbreakDermatologyGeneral Medicinemedicine.disease_causebiology.organism_classificationVirologyPandemicMedicinebusinessCoronavirus InfectionsBetacoronavirusCoronavirusDermatologic Therapy

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Prevalence and 30-Day Mortality in Hospitalized Patients With Covid-19 and Prior Lung Diseases.

2021

Patients with pre-existing respiratory diseases in the setting of COVID-19 may have a greater risk of severe complications and even death.A retrospective, multicenter, cohort study with 5847 COVID-19 patients admitted to hospitals. Patients were separated in two groups, with/without previous lung disease. Evaluation of factors associated with survival and secondary composite end-point such as ICU admission and respiratory support, were explored.1,271 patients (22%) had a previous lung disease, mostly COPD. All-cause mortality occurred in 376 patients with lung disease (29.5%) and in 819 patients without (17.9%) (Previous lung disease is a risk factor for mortality in patients with COVID-19.…

HOPE-COVID-19 Health Outcome Predictive Evaluation for COVID-19Respiratory diseasesOriginal30-Day mortalityenfermedades respiratoriasACE2 angiotensin converting enzyme IIlaw.invention0302 clinical medicineCQ/HCQ chloroquine/hydroxychloroquinelawCOPDrespiratory diseasesPrognosisICU intensive care unitIntensive care unitSTROBE strengthening the reporting of observational studies in epidemiologypronósticomedicine.anatomical_structureEPOCCohort studyPulmonary and Respiratory Medicinemedicine.medical_specialty30-day mortalityRT-PCR real time reverse transcriptase-polymerase chain reactionSARS-CoV-2 severe acute respiratory syndrome coronavirus 2WHO World Health OrganizationMERS middle east respiratory syndrome03 medical and health sciencesInternal medicinemedicineCOPDCOVID-19 2019 novel coronavirusRisk factorIQR interquartile rangeLungmortalidad a 30 díasbusiness.industryFEV1 forced expiratory volume in one secondCOVID-19Retrospective cohort studymedicine.diseaseHR hazard ratioICS inhaled corticosteroidsCI confidence intervalCoronavirusCOPD chronic obstructive pulmonary disease030228 respiratory systemRespiratory failureILD interstitial lung diseaseMiddle East respiratory syndromeprognosisHFNC high flow nasal cannulabusiness

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Immune responses during COVID-19 infection

2020

International audience; Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics. The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health care and economic systems across the world. This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. While protective humoral and cellular immune responses are usually m…

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Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning.

2021

Coronavirus disease 2019 (COVID-19) is a major threat worldwide due to its fast spreading. As yet, there are no established drugs available. Speeding up drug discovery is urgently required. We applied a workflow of combined in silico methods (virtual drug screening, molecular docking and supervised machine learning algorithms) to identify novel drug candidates against COVID-19. We constructed chemical libraries consisting of FDA-approved drugs for drug repositioning and of natural compound datasets from literature mining and the ZINC database to select compounds interacting with SARS-CoV-2 target proteins (spike protein, nucleocapsid protein, and 2′-o-ribose methyltransferase). Supported by…

0301 basic medicineSimeprevirArtificial intelligencevirusesMERS Middle East Respiratory SyndromeHealth InformaticsBiologyMachine learningcomputer.software_genremedicine.disease_causeAntiviral AgentsArticleWHO World Health OrganizationAUC area under the curve03 medical and health sciences0302 clinical medicinessRNA single-stranded RNA virusmedicineChemotherapyHumansSARS severe acute respiratory syndromeCOVID-19 coronavirus disease 2019CoronavirusNatural productsVirtual screeningACE2 angiotensin converting enzyme 2Drug discoverybusiness.industrySARS-CoV-2COVID-19LBE lowest binding energyFDA Food and Drug AdministrationROC receiver operating characteristicComputer Science ApplicationsHIV human immunodeficiency virusMolecular Docking SimulationDrug repositioning030104 developmental biologyDrug developmentSevere acute respiratory syndrome-related coronavirusParitaprevirInfectious diseasesRespiratory virusArtificial intelligenceSupervised Machine Learningbusinesscomputer030217 neurology & neurosurgeryComputers in biology and medicine

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Statistical Explorations and Univariate Timeseries Analysis on COVID-19 Datasets to Understand the Trend of Disease Spreading and Death

2020

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0301 basic medicinetransmission ratepopulationSevere Acute Respiratory Syndromemedicine.disease_causelcsh:Chemical technologyBiochemistryRNNDisease OutbreaksAnalytical Chemistry0302 clinical medicinePandemiclcsh:TP1-1185030212 general & internal medicineInstrumentationVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550Coronaviruskeraseducation.field_of_studypublic healthartificial intelligenceAtomic and Molecular Physics and OpticsRegressionmachine learningGeographySevere acute respiratory syndrome-related coronavirusstatisticsMiddle East Respiratory Syndrome Coronaviruscommunity diseaseregressionCoronavirus InfectionsLSTMPneumonia ViralPopulationWorld Health OrganizationArticleBetacoronavirusspread factor03 medical and health sciencesCode (cryptography)medicineAnimalsHumansElectrical and Electronic EngineeringeducationPandemicsmeasurable sensor dataalgorithmSARS-CoV-2ICDUnivariatedeep learningOutbreakCOVID-19medicine.diseasehypothesis testpython030104 developmental biologycorrelationCatsMiddle East respiratory syndromeCattleDemographySensors

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